September 15, 2024
2024 Research Proposal Elements / Application Template
Submit via email to info@nnecos.org.
The Northern New England Clinical Oncology Society (NNECOS) is seeking proposals for investigative projects of value to the Northern New England community of cancer care providers. Our goal is to fund one or more proposals, up to a total of $20,000 for the September 2024 application cycle. Eligible candidates will be a current NNECOS active or fellow/trainee member in good standing. Fellows and members of the interdisciplinary-care team are strongly encouraged to apply. Projects should align with our mission to promote the highest quality care for patients with cancer and blood disorders in our region. Preference will be given to projects promoting collaboration among NNECOS institutions (academic and community).
Proposals should be prepared in 11-point font, Arial, or Times New Roman, utilizing one-inch margins.
PROPOSAL ELEMENTS
Page 1 – Abstract: 250 words or less stating the Background, Hypothesis, Proposed Methods, and Interpretation of Results.
Pages 2-3 - Body (Submissions exceeding two pages will be returned to the PI):
Section 1 - Introduction with Hypothesis and Objective(s) – 2 SHORT paragraphs. (NOTE: The Review committee is MORE interested in Methods, Statistics and Analysis of Results)
Section 2 - Methods with Statistics (Except for small pilot/feasibility studies, statistics should be provided to support sample sizes.)
Section 3 - Analysis of Results – What do you expect the results to show and how will you interpret the results?
Page 4 - Budget, References
Budget: Must be clearly outlined. Materials and funds for services of collaborating facility employees required in the operations of a project (i.e., research coordinator, statistician, etc., in alignment with national averages for their role) are examples of items to include in the budget. If the proposal is part of a larger project, the total amount of funding and its sources should be disclosed. Indirect costs and salary support for academic attending physicians and private practice providers should not be included.
References: Pertinent journal and abstract references to support proposal
NOTIFICATION
Awardees will be notified in approximately six to eight weeks, be required to submit progress reports to NNECOS, submit the results of the research for poster presentation and if invited, present a final report of the research to the NNECOS annual meeting.
APPLICATION DEADLINE!
Completed applications must be received via email no later than 11:59pm on the stated deadline.
Please note NNECOS is unable to fund indirect costs or investigator salaries as part of the grant budget.
Congratulations to principal investigators, Dr. Caroline Hesko and Dr. Sakshi Jasra on the receipt of a NNECOS Research Grant for their study, Improving Adolescent and young adult cancer clinical trial enrollment through improvement science: a pediatric and medical oncology partnership!
Congratulations to principal investigator, Dr. Nirav Kapadia, and his team of collaborators at Norris Cotton Cancer Center and the Dartmouth Institute for Clinical Practice and Health Policy on the receipt of a NNECOS Research Grant for your study, "Defining Financial Toxicity Among Rural Radiation Oncology Patients". We are pleased to support this important work!
Results of Dr. Kapadia's study were reported at the American Association for Cancer Research Conference poster session.
Congratulations, Dr. Muhaad Zubair Afzal, Hematology-Oncology Fellow at Norris Cotton Cancer Center, on the awarding of a NNECOS research grant for your pilot study, "The Impact of Lymphodepletion on Myeloid-Derived Suppressor Cells and Other Immune Modulators in Patients Receiving Chimeric Antigen Receptor (CAR) T-cell Therapy: A Clinical Pilot Study."
Congratulations to Dr. Alissa Thomas, Associate Professor of Neurological Sciences at the University of Vermont on being awarded a NNECOS Research Grant for her project, "Venous Thromboembolism Prevention in Outpatients with Glioma (VTE-POG)". This two-year project will build on data from a previous 10 patient pilot study, with the goal of demonstrating safety of apixaban for VTE prevention.
The study aims to define the influence of clinical factors and treatment strategies on the risk of cardiovascular disease in myelodysplastic syndromes using epidemiologic database analysis. NNECOS funding was instrumental to launch the project and conduct preliminary analysis. These results contributed to secure funding for the project in the next 2 years from the Hemostasis and Thrombosis Research Society, as well as the investigator’s enrollment in the Clinical Research Training Institute Program from the American Society of Hematology, guaranteeing strong support for subsequent analysis methodology. Congratulations, Dr. Adrianzen Herrera!
Since the program’s inception in 2008, the NNECOS Research Funding Program has awarded more than $200,000 to worthy projects of value to the Northern New England region.
CONGRATULATIONS, DR. GILLETT!
Sarah Gillett, Md, PhD Co-Principal Investigator Alissa A. Thomas, MD Co-Investigator Hibba Rehman, MD Dr. Gillett's study aims to define the incidence of cognitive impairment on ICI and to examine trajectories of cognitive scores for patients on ICI. |
Three University of Vermont Faculty Projects
Awarded NNECOS Research Grants in 2021
Shahid S. Ahmed, MD, Larner College of Medicine, UVM Cancer Center Dr. Ahmed's study hypothesizes that the urinary microbiome directly modulates resident bladder T-cells. Differences in the microbial taxonomy and its diversity will affect the TCR repertoire leading to the development of immune-escaped bladder cancers. We look forward to the outcomes of this pilot study and the potential to inform future strategies in the prevention and treatment of bladder cancer. |
Diego Andrianzen, M.D., Assistant Professor of Medicine and Neil Zakai, M.D., M.Sc., Associate Professor of Medicine Hematology/Oncology Division, Larner College of Medicine at the University of Vermont The primary objective of this study is to determine the sociodemographic and patient-specific clinical risk factors associated with increased risk of CVD and cardiovascular mortality in patients with MDS. The secondary objective is to determine the impact of MDS-specific therapeutic interventions (hypomethylating agents, iron chelation and growth factors) on hazard for new CVD or cardiovascular mortality in MDS patients. Results published in Blood (2021) 138 (Supplement 1): 3060. https://doi.org/10.1182/blood-2021-146683 |
Previous NNECOS Research Grant Recipients
VTE Risk Assessment and Prevention in Cancer Patients in the Community Oncology Setting
Learn more about the work of this group Successful Model for Guideline Implementation to Prevent Cancer-Associated Thrombosis: Venous Thromboembolism Prevention in the Ambulatory Cancer Clinic
New! Research Published
The Lancet - Regional Health Americas
https://authors.elsevier.com/sd/article/S2667193X24001935
Congratulations to the 2017 NNECOS Research Grant Recipients
NNECOS awarded a total of $45,694 in research grants to 2017 applicants
2017 Recipients
Past Projects Funded Include:
Litterini A, Cavanaugh J, Fieler V, Lee JQ. Differential Effects of Cardiovascular and Resistance Exercise on Functional Mobility in Individuals with Advanced Cancer: A Randomized Trial. Arch Phys Med Rehabil. 2013;94:2329-35.
Litterini, A and Lee, J. “Exercise for Individuals with Metastatic Cancer.” APTA 2013 Combined Sections Meeting, Oncology Section Platform Presentation, San Diego, CA, 2013.
Litterini, A., and Fieler, V. “Differential Effects of Cardiovascular and Resistance Exercise on Functional Mobility in Individuals with Advanced Cancer: A Randomized Trial.” Poster Presentation, 2015 New England Cancer Survivorship Research Symposium, Harvard Medical School/ Dana-Farber Cancer Institute in Boston, MA, on April 2, 2015. Available [on-line]: http://dune.une.edu/pt_facpost/4
Role of prostaglandin pathways in radiotherapy-induced mucositis.
Steven M. Grunberg, Madhuri V. Vithala, Margaret Vizzard, Nathan Bradley Adams, Havaleh Marie Gagne, William Brundage, and Takamaru Ashikaga; Journal of Clinical Oncology 2013 31:15_suppl, e20509-e20509
- Emery, Ivette et al. Expression and Function of ABCG2 and XIAP in Glioblastomas. Journal of NeuroOncology May 2017. Volume 133(1) 47-57
Michael Y. Cho, Aderonke Ajala, Lauren T. Salvatore, Deborah L. Ornstein, Monic R. Drescher,
Thrombin Generation As a Predictive Biomarker for Venous Thromboembolism in Patients with Pancreatic and Lung Cancer Undergoing Systemic Therapy, Blood, Volume 130, Supplement 1,
2017, Page 1103, ISSN 0006-4971,https://doi.org/10.1182/blood.V130.Suppl_1.1103.1103.